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By replenishing glutathione levels, either through supplementation or enhancing its production, the antioxidant properties of glutathione help reduce oxidative stress, neuroinflammation, and neuronal damage, thereby slowing disease progression and improving symptoms in various neurological disorders

As we noted earlier, the risk of toxicity with vitamin B12 is low because its water soluble

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Therefore, this section focused on the progress of clinical trials for treating amino acid metabolism in diseases

Mitochondrial biosensors

In this case, the authors concluded that a 1% simvastatin cream directly onto skin lesions, but not torvastatin, inhibits disease progression (Niezgoda et al., 2024)